Перегляд за автором "Skrypkina, I.Ya."

Сортувати за: Порядок: Результатів:

  • Amphiphysin 1 and 2 interact with latent membrane protein 2A of Epstein-Barr virus and regulate its exosomal secretion 
    Dergai, O.V.; Dergai, M.V.; Tsyba, L.O.; Yaruchik, A.M.; Rynditch, A.V.; Skrypkina, I.Ya. (Вiopolymers and Cell, 2012)
    Латентный мембранный белок 2А вируса Эпштейна-Барр является ключевым регулятором латентной фазы вирусной инфек- ции. Цель. Идентифицировать белки, способные связываться с пролин-обогащенными мотивами LMP2A. Методы. Анализ ...
  • Ca²⁺ does not affect the binding properties of ITSN1 EH domains 
    Morderer, D.Ye.; Rymarenko, O.V.; Skrypkina, I.Ya.; Rynditch, A.V. (Вiopolymers and Cell, 2014)
    ITSN1 is an endocytic scaffold protein implicated in synaptic functioning. Ca²⁺ is known to be important for endo- cytosis in both pre- and post-synaptic terminals. ITSN1 contains two EH (Eps15 homology) domains which ...
  • Ca/calmodulin-dependent phosphorylation of endocytic scaffold ITSN1 
    Morderer, D.Ye.; Nikolaienko, O.V.; Skrypkina, I.Ya.; Rymarenko, O.V.; Kropyvko, S.V.; Tsyba, L.O.; Rynditch, A.V. (Вiopolymers and Cell, 2014)
    ITSN1 is an endocytic scaffold protein with a prominent function in synaptic transmission. It is known that Ca signaling is crucial for the regulation of synaptic proteins functioning. Aim. Checking the possibility of ...
  • Identification and functional analysis of an alternative promoter of human intersectin 1 gene 
    Kropyvko, S.V.; Tsyba, L.O.; Skrypkina, I.Ya.; Rynditch, A.V. (Вiopolymers and Cell, 2010)
    Intersectin 1 (ITSN1) gene encodes an evolutionarily conserved adaptor protein that functions in clathrin-mediated endocytosis, cell signalling, apoptosis and cytoskeleton rearrangements. Its expression is characterized ...
  • Interaction of ubiquitin ligase CBL with LMP2A protein of Epstein-Barr virus occurs via PTB domain of CBL and does not depend on adaptor ITSN1 
    Dergai, O.V.; Dergai, M.V.; Gudkova, D.O.; Tsyba, L.O.; Skrypkina, I.Ya.; Rynditch, A.V. (Вiopolymers and Cell, 2013)
    Aim. Previously Latent membrane protein 2A (LMP2A) of Epstein-Barr virus was found to be ubiquitylated by CBL ubiquitin ligase but no direct interaction of LMP2A with CBL was reported. We aimed to explore this interaction ...
  • ITSN1 and Ruk/CIN85 colocalized to clathrin-coated pits in MCF-7 cells 
    Nikolaienko, O.V.; Skrypkina, I.Ya.; Tsyba, L.O.; Drobot, L.B.; Rynditch, A.V. (Вiopolymers and Cell, 2009)
    Activation of receptor tyrosine kinases (RTK) by corresponding ligands results not only in signal propagation, but also initiates a number of processes, such as clathrin-mediated endocytosis, which precisely regulate ...
  • ITSN protein family: regulation of diversity, role in signalling and pathology 
    Tsyba, L.O.; Dergai, M.V.; Skrypkina, I.Ya.; Nikolaienko, O.V.; Dergai, O.V.; Kropyvko, S.V.; Novokhatska, O.V.; Morderer, D.Ye.; Gryaznova, T.A.; Gubar, O.S.; Rynditch, A.V. (Вiopolymers and Cell, 2013)
    Adaptor/scaffold proteins of the intersectin (ITSN) family are important components of endocytic and signalling complexes. They coordinate trafficking events with actin cytoskeleton rearrangements and modulate the activity ...
  • Novel isoform of adaptor protein ITSN1 forms homodimers via its C-terminus 
    Dergai, M.V.; Dergai, O.V.; Tsyba, L.O.; Novokhatska, O.V.; Skrypkina, I.Ya.; Rynditch, A.V. (Вiopolymers and Cell, 2011)
    Aim. Previously we have identified a novel isoform of endocytic adaptor protein ITSN1 designated as ITSN1- 22a. Western blot revealed two immunoreactive bands of 120 and 250 kDa that corresponded to ITSN1-22a. The goal ...
  • Phylogenetic analysis of two Ukrainian isolates of Wheat streak mosaic virus 
    Mishchenko, L.T.; Dunich, A.A.; Skrypkina, I.Ya.; Kozub, N.O. (Вiopolymers and Cell, 2019)
    The study of molecular characteristics and, in particular, the nucleotide (nt) and amino acid (aa) sequences of the viral genomes, is necessary to know the changes in their geographical range, phylogenetic relationships, ...
  • RTK signaling regulator SPRY2 associates with endocytic adaptor ITSN1 in vivo 
    Novokhatska, O.V.; Skrypkina, I.Ya.; Dergai, M.V.; Tsyba, L.O.; Rynditch, A.V. (Вiopolymers and Cell, 2012)
    Передача митогенного сигнала от RTK (рецепторных тирозиновых киназ) тесно связана с эндоцитозом, регулирующим ее точность. Интерсектин 1 (ITSN1) – эволюционно-консервативный адапторный белок, вовлеченный в самые ранние ...